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Callus Culture for the Production of Therapeutic Compounds

Received: 20 September 2019     Accepted: 8 October 2019     Published: 23 October 2019
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Abstract

Plant-derived compounds retain a special place in the treatment of various diseases across the world. Their application cuts across every class of disease, where they are found to be often equal or of greater potency, safer and cheaper than so-called "orthodox" medicines. These advantages have led to great interest in the use of callus culture as a biotechnological tool for the harnessing of these useful therapeutic compounds. Callus culture techniques aim to increase the yield of active constituents in cultured plant cells and to produce novel products on a large scale. These techniques have been applied to produce various classes of therapeutic compounds from diverse plant species through empirical determination of ideal culture conditions and other methods. This review presents at a glance the recent advances being made in the field of callus culture for the production of therapeutic compounds, with the aim of showing that it is time for the full potentials of callus culture to be exploited on a scale that will prove a useful weapon in the arsenal of clinical therapeutics.

Published in American Journal of Plant Biology (Volume 4, Issue 4)
DOI 10.11648/j.ajpb.20190404.14
Page(s) 76-84
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Callus Culture, Plant Growth Regulator, Elicitor, Precursor, Anticancer, Antiviral, Antioxidant, Therapeutic Nanoparticles

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    Emmanuel Dabuwar Benjamin, Gali Adamu Ishaku, Fartisincha Andrew Peingurta, Abolade Samuel Afolabi. (2019). Callus Culture for the Production of Therapeutic Compounds. American Journal of Plant Biology, 4(4), 76-84. https://doi.org/10.11648/j.ajpb.20190404.14

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    Emmanuel Dabuwar Benjamin; Gali Adamu Ishaku; Fartisincha Andrew Peingurta; Abolade Samuel Afolabi. Callus Culture for the Production of Therapeutic Compounds. Am. J. Plant Biol. 2019, 4(4), 76-84. doi: 10.11648/j.ajpb.20190404.14

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    AMA Style

    Emmanuel Dabuwar Benjamin, Gali Adamu Ishaku, Fartisincha Andrew Peingurta, Abolade Samuel Afolabi. Callus Culture for the Production of Therapeutic Compounds. Am J Plant Biol. 2019;4(4):76-84. doi: 10.11648/j.ajpb.20190404.14

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  • @article{10.11648/j.ajpb.20190404.14,
      author = {Emmanuel Dabuwar Benjamin and Gali Adamu Ishaku and Fartisincha Andrew Peingurta and Abolade Samuel Afolabi},
      title = {Callus Culture for the Production of Therapeutic Compounds},
      journal = {American Journal of Plant Biology},
      volume = {4},
      number = {4},
      pages = {76-84},
      doi = {10.11648/j.ajpb.20190404.14},
      url = {https://doi.org/10.11648/j.ajpb.20190404.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajpb.20190404.14},
      abstract = {Plant-derived compounds retain a special place in the treatment of various diseases across the world. Their application cuts across every class of disease, where they are found to be often equal or of greater potency, safer and cheaper than so-called "orthodox" medicines. These advantages have led to great interest in the use of callus culture as a biotechnological tool for the harnessing of these useful therapeutic compounds. Callus culture techniques aim to increase the yield of active constituents in cultured plant cells and to produce novel products on a large scale. These techniques have been applied to produce various classes of therapeutic compounds from diverse plant species through empirical determination of ideal culture conditions and other methods. This review presents at a glance the recent advances being made in the field of callus culture for the production of therapeutic compounds, with the aim of showing that it is time for the full potentials of callus culture to be exploited on a scale that will prove a useful weapon in the arsenal of clinical therapeutics.},
     year = {2019}
    }
    

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    T1  - Callus Culture for the Production of Therapeutic Compounds
    AU  - Emmanuel Dabuwar Benjamin
    AU  - Gali Adamu Ishaku
    AU  - Fartisincha Andrew Peingurta
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    N1  - https://doi.org/10.11648/j.ajpb.20190404.14
    DO  - 10.11648/j.ajpb.20190404.14
    T2  - American Journal of Plant Biology
    JF  - American Journal of Plant Biology
    JO  - American Journal of Plant Biology
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    AB  - Plant-derived compounds retain a special place in the treatment of various diseases across the world. Their application cuts across every class of disease, where they are found to be often equal or of greater potency, safer and cheaper than so-called "orthodox" medicines. These advantages have led to great interest in the use of callus culture as a biotechnological tool for the harnessing of these useful therapeutic compounds. Callus culture techniques aim to increase the yield of active constituents in cultured plant cells and to produce novel products on a large scale. These techniques have been applied to produce various classes of therapeutic compounds from diverse plant species through empirical determination of ideal culture conditions and other methods. This review presents at a glance the recent advances being made in the field of callus culture for the production of therapeutic compounds, with the aim of showing that it is time for the full potentials of callus culture to be exploited on a scale that will prove a useful weapon in the arsenal of clinical therapeutics.
    VL  - 4
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Author Information
  • Department of Pharmaceutical Microbiology and Biotechnology, University of Jos, Jos, Nigeria

  • Department of Pharmaceutical Microbiology and Biotechnology, University of Jos, Jos, Nigeria

  • Department of Science Laboratory Technology, Modibbo Adama University of Technology, Yola, Nigeria

  • Biotechnology and Genetic Engineering Advanced Laboratory, Sheda Science and Technology Complex, Abuja, Nigeria

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